Association of the severity and pattern of pituitary adenoma-related headache with the size and type of adenoma

Introduction: Headache is one of the essential symptoms pituitary adenoma associated with tumor and patient’s characteristics. The pattern adenoma-related headaches varies widely can significantly impact quality life. Objectives: We aimed to investigate severity in patients Iran. Patients Methods: In this cross-sectional study, we investigated 109 an initial complement headaches. diagnosis was confirmed. Patients’ demographic characteristics [e.g., gender, body mass index (BMI), age] (e.g., subtype size tumor) were collected by interview, clinical examination, imaging. measured headache using Impact Test-6 (HIT-6) questionnaire version 1.1. Results: our most common prolactinoma, followed non-functional growth hormone (GH)-releasing adrenocorticotropic (ACTH)-releasing adenomas. Functional more women; however, incidence men (61%), indicating correlation between gender (P=0.008). Most tumors functional microadenomas (69%), while macroadenomas primarily (50%). HIT-6 scores demonstrated that had higher prolactinoma experienced severe than other subtypes (P=0.003). Conclusion: Our study revealed significant effects type on headaches, as muscular Additionally, hormone-releasing function plays a vital part advent